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Cell Biology International (1998) 22, 345349 (Printed in Great Britain)
CREATINE KINASE AND CREATINE KINASE ISOENZYME RESPONSES TO HEAT STRESS
S.E TERBLANCHE and W NEL
Department of Biochemistry and Microbiology, University of Zululand, Private Bag X1001, Kwa Dlangezwa, 3886, South Africa
During this investigation the effects of heat acclimation and exercise on creatine kinase and creatine kinase BB isoenzyme responses in various tissues and serum of male Sprague–Dawley rats were ascertained. Forty rats were randomly divided into two groups of 20 rats each. One group was housed at 22±1°C and the other at 33±1°C. Each of the two groups were subdivided into two subgroups of ten rats each. One subgroup of each group was subjected to a programme of treadmill running of progressive intensity over a period of 6 weeks at the temperature at which it was housed while the other served as a resting control. At the end of the acclimation programme the rats were running at 23
Key words: heat acclimation, exercise, creatine kinase, creatine kinase isoenzymes.
f1*To whom correspondence should be addressed: S. E. Terblanche, Department of Biochemistry and Microbiology, University of Zululand, Private Bag X1001, Kwa Dlangezwa, 3886, South Africa.
Received 28 January 1998; accepted 28 April 1998doi:10.1006/cbir.1998.0267