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Cell Biology International (2001) 25, 821–824 (Printed in Great Britain)

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TRANSCRIPTION OF Fcγ RECEPTORS IN DIFFERENT RAT LIVER CELLS

Torunn Løvdal and Trond Berg^f1

Division of Molecular Cell Biology, Department of Biology, University of Oslo, P.O. Box 1050, Blindern, 0316, Oslo, Norway

Abstract

Expression of Fcγ-receptors (FcγRs) in different liver cells is poorly characterised. In the present study, transcription of FcγRs in different rat liver cells was examined by means of Northern blot analysis and reverse transcriptase-polymerase chain reactions. We found that both Kupffer and liver endothelial cells produce mRNA for FcγRIIB2, FcγRIII and the γ-chain, whereas the level of FcγRIIB1 mRNA is negligible. In contrast, parenchymal cells produce no FcγR mRNA.

Key words: Fc receptor, Kupffer cells, liver endothelial cells.

^f1To whom correspondence should be addressed. Fax: +47 22 85 4605; E-mail:trond.berg@bio.uio.no

Received 8 February 2001; accepted 27 February 2001