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Cancer Cell death Cell cycle Cytoskeleton Exo/endocytosis Differentiation Division Organelles Signalling Stem cells Trafficking
Cell Biology International (2001) 25, 931–934 (Printed in Great Britain)
SUBSTRATE-INDUCED POLARISATION OF CULTURED EPITHELIOCYTES AND FIBROBLASTS: NON-REACTIVITY OF RAS-TRANSFORMED CELLS
Tatjana G. Moizhess and Jury M. Vasilievf1
Cancer Research Centre of Russian Academy of Medical Sciences, Kashirskoe Shosse, 24, 115478, Moscow, Russia


Abstract

Non-transformed epitheliocytes and fibroblasts undergo modulations between the less polarised and more polarised phenotypes depending on the nature of the substrate. In contrast, transformed cells express polarised phenotype regardless of the substrate.


Key words: cell shape, cell polarisation, substrates, morphometry.

f1To whom correspondence should be addressed. Fax: 7(095)-324-12-05; E-mail:vasiliev@cityline.ru


Received 6 February 2001; accepted 15 February 2001

doi:10.1006/cbir.2001.0776


ISSN Print: 1065-6995
ISSN Electronic: 1095-8355
Published by Portland Press Limited on behalf of the International Federation for Cell Biology (IFCB)