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Cell Biology International (2007) 31, 1396–1399 (Printed in Great Britain)

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Tumour necrosis factor-α receptor 1 polymorphisms and serum soluble TNFR1 in early spontaneous miscarriage

Xue‑Wen Yu^a*, Xu Li^b, Yong‑Hui Ren^a and Xue‑Cheng Li^a

^aCenter of Maternal and Child Health, First Affiliated Hospital of the Medical School in Xi'an Jiaotong University, Xi'an, China
^bCenter of Medical Molecular, First Affiliated Hospital of the Xi'an Jiaotong University Medical School, Xi'an, China

Abstract

The study investigated the association of TNFR1 gene polymorphism with early recurrent spontaneous miscarriage (ERSM) in Chinese women, and soluble TNFR1 (sTNFR1) expression in ERSM women.

Key words: Early recurrent spontaneous miscarriage (ERSM), Tumour necrosis factor receptor 1 (TNFR1), Soluble TNFR1(sTNFR1), Gene polymorphism, Single nucleotide polymorphisms (SNPs).

^*Corresponding author. Tel.: +86 29 8532 3223; fax: +86 29 8523 5492.

Received 9 May 2007/3 June 2007; accepted 6 June 2007