|Cancer||Cell death||Cell cycle||Cytoskeleton||Exo/endocytosis||Differentiation||Division||Organelles||Signalling||Stem cells||Trafficking|
Cell Biology International (2010) 34, S47 (Printed in Great Britain)
Clinicopathologic features of gallbladder carcinosarcoma - adenocarcinoma and angiosarcoma
Bo Hu1, Guangtao Xu2, Ziwan Zhu2, Yang Zheng2 and Hangbin Yu2
1Department of Pathology, Jiaxing Traditional Chinese Medical Hospital, Jiaxing, Zhejiang, China, and 2Department of Pathology, Medical College of Jiaxing University, Jiaxing, Zhejiang, China
We found a rare case of gallbladder carcinosarcoma composed of adenocarcinoma and angiosarcoma. A 67-year-old man was treated in hospital, we studied this disease with its clinical data, histopathology and immunohistochemistry, and relevant existing literature, in order to characterize of this disease. The size of gallbladder is 10.0cm × 5.0cm × 4.5cm, and the tumor had infiltrated into serosa of gallbladder, but non-existent in the liver. Histopathology and immunohistochemistry showed infrequent adenocarcinoma and angiosarcoma simultaneously coexisted, and no transitional areas were detected between carcinoma and sarcoma. Gallbladder carcinosarcoma with coexistence of adenocarcinoma and angiosarcoma is a rare tumor with high malignant neoplasm, which needs to be discriminated from several other diseases. The stage of the tumor is an important prognostic factor in carcinosarcoma of gallbladder and it may be used for prognosis.
Published online 1 August 2010, doi:10.1042/CBI034S047d
© The Author(s) Journal compilation © 2010 Portland Press Limited